Platelet cell-surface protein disulphide-isomerase mediated S-nitrosoglutathione consumption
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چکیده
منابع مشابه
Platelet cell-surface protein disulphide-isomerase mediated S-nitrosoglutathione consumption.
S-nitrosothiols (RSNOs) regulate several aspects of platelet physiology including inhibition of activation, adhesion and aggregation. PDI (protein disulphide-isomerase) has recently been found to be localized to the cell surface, where it exhibits both disulphide-exchange and denitrosation activities. The disulphide-exchange activity of PDI has been linked to aspects of platelet aggregation. Th...
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ژورنال
عنوان ژورنال: Biochemical Journal
سال: 2004
ISSN: 0264-6021,1470-8728
DOI: 10.1042/bj20040759